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Mario text art copy and paste2/17/2024 Even if just one person was saved from losing hours and hours of work, my mission is accomplished. You never know if today would be the day you lose everything. I would estimate more than 40% of scratchers have passwords that are hard to guess by a human, but easy to guess by a computer. Here you get a large collection of mario text and mario ascii, around 100+ mario art at single location with its true meaning. Remember, the goal is to create a password that is strong, unique, and difficult for others to guess. Regular updates: Regularly change your passwords to stay ahead of potential security threats. coquette dog cat sanrio puppy night aesthetic symbols dot art pretty esthetic emo vamp sparkle toy dog kitten felidae poodle pet. its gross please let them stay kids, there are other websites for that. Randomness: Use a random password generator to create a unique and unpredictable password. thorny ppl please get out of here, kids who are like 9 years old are on here looking for combos and can see whats posted. Passphrases: A phrase made up of random words, numbers, and symbols, as these can be easier to remember but still secure. Also, avoid using the same password for multiple accounts. Uniqueness: Don't use easily guessable information like your name, address, or date of birth. Complexity: Combination of upper and lowercase letters, numbers, and symbols to make it harder to crack. A password that is at least 12 characters long. Now you should be able to use Scratch 2.0 on your computer!Īsk yourself, if you were hacked and lost hours, upon hours of work, would you regret not having a strong password that only takes 5 minutes to make? I s i t t i m e t o u p d a t e y o u r p a s s w o r d ? Here are some tips to make a strong password: Length: The longer the password, the stronger it is. Original emoji you can use anywhere Register your own custom emoji or use emoji from other users online and in apps. Download Scratch 2.0 here: Now, go into the Flash Player, and press File > Open, and then select the. Do not download the debugger, just the projector. If you can't download the normal 2.0 editor, try these steps: Download the Adobe Flash Player Projecter here: (sadly they took it down recently from the official site, thanks to the Internet Archive for archiving it) Select the program that is right for your device. current, super compressed portion of captain quazar fmv - another segment of the captain quazar fmv - captain quazar sussy lookie - just a maroon square - default scratch cat avatar Sorry, you have to wait 60 seconds between posts. all of my pfp's: - mario exe creepysussy bakapasta. These super mario fonts work as an online font changer for Instagram.Quote of the day: highlight this text and press ctrl+shift+down/up arrow keys to see the rest of my beefy signature. It acts like a text style changer for the input text by the user. Dont forget to click the spacesunderscores button to fill the white space with underscore characters so that when you paste it somewhere, it doesnt collapse all the spaces. It can be used as a name font changer on social media platforms. Welcome to the textart.sh collection of peen text art You can copy and paste these art pieces using the buttons below each piece. Super mario Text font changer is in a way unique because it is a free font changer available on the internet. While on mobile these super mario fonts can be used by just pressing the screen long enough to display an option "paste" and then clicking it. This can be used just by pressing "ctrl+V" on your keyboard. Super mario Font Changer Copy Paste as the name suggests easily allows you to copy your converted fonts to clipboard. Not only do they add a professional look, but the right font can also help draw attention to certain words or phrases. Try this super mario font generator for your business logo design. Fancy fonts online is the advanced tool that converts your entered text to cool super mario fonts. If you are wondering where you will find these fancy texts, fancyfonts.top is the tool. Font change has become a trend nowadays on social media, people use copy and paste super mario fonts for every caption and comments. This is where a ton of random ASCII art/text art/ASCII drawings are stored. This tool has the capacity to combine all these fonts with special characters and symbols and then display the best super mario fonts. There are many fancy super mario texts that I bet you haven’t seen anywhere. Super mario Font changer is a specifically designed tool to change font style to whichever fancy fonts you need. The Best Free super mario Font generator for your Tattoos, Designs and social media
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Solitaire free game2/17/2024 The Palace’s RangeĪlong with Solitaire online, we offer various popular and classic card games: How about playing Spider Solitaire instead of Klondike for a change? In doing so, you get to adjust the classic Solitaire game to your taste – go easy or go for a challenge! Perhaps, you will even discover new variations with different dynamics. Our numerous custom rules are interesting, too! You can select and combine them as you wish, e.g., Relaxed, Double, Joker. As a Premium player, you can create your own tables with selected rules and define conditions for joining you. The premium features are much enjoyed by experienced players at the Palace. If you have been playing at the Palace for a while, we recommend the Premium membership. If you want to learn more about the origin of the game, click here. So much for the modern possibilities of playing Solitaire. The interface adjusts automatically and displays the cards in optimal size. Especially when on the go, you are free to switch between playing with one or two hands. Play Solitaire online as you prefer – using a PC, laptop, tablet, or smartphone! Solitaire Palace is available cross-device and cross-platform:Īll our games support portrait and landscape mode on mobile devices. You get to focus on solving the game while the computer arranges the playing field and enforces rules. That is likely due to the computer’s strength in reliably and correctly fulfilling boring tasks. Luckily, there is an easy fix: Play free and digitally at the Solitaire Palace! Solitaire gained its massive popularity only after the PC was developed. That requires extra focus and attention to not mix up the playing field. Over the span of a Solitaire game, many cards are moving over and over. As there are also countless Solitaire variations, with variations in the setup and difficulty level, we offer you plenty of custom rules. While it sounds easy at first, it packs a punch! Some classic Solitaire games are difficult to solve, and, rarely, one cannot be solved. Informative explanations of individual Solitaire terms can be found in our alphabetical Solitaire glossary. The game is solved by placing all cards correctly sorted in the foundation.Įach step of the game follows specific rules, which you can find in detail in our free Solitaire manual. Now, you must combine the revealed cards tactically in order to reveal and free all cards on the table. The stock holds all remaining cards face-down to draw from. In the tableau, you place multiple card piles with each top card revealed. Here is an outline of the bedrock principles: You need one player, 52 French-suited cards, and a table with three zones, called tableau, foundation, and stock. Klondike Solitaire is one of many solitaire games, which are also known as patience games in Europe.
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Valorant crosshair settings pro2/16/2024 Having played VALORANT since the game came out, I can see big similarities when it comes to CS:GO in regards to the gunplay and overall gameplay. Besides this, I have spent many hours analyzing professional players and looking at their settings, including their crosshair settings. I was at the Master rank in Overwatch, while not the highest rank, still very decent and among the top 5% best if I am not completely wrong. I am a long time CS:GO player ranked Global Elite (the highest rank, around the top best 1% of players). In CS:GO, people have been looking for the ultimate crosshair since the game came out.īefore we dig into this guide, I just want to quickly tell about why I believe that I am qualified for giving advice on this matter. VALORANT is a highly competitive FPS game, like CS:GO had a baby with Overwatch or Team Fortress. That said, we will try to look into what professional players and popular streamers use as their crosshair settings. One thing to consider is that the crosshair settings depends on personal preference. VALORANT gives you the ability to select and tweak your own crosshair in many ways, which means that there are almost unlimited options when it comes to configuring your crosshair. Since aiming is such an essential part of VALORANT, having a good crosshair is also essential if you want to aim better and get more eliminations. If you want a comprehensive list of all pro player crosshairs, check out Pro Setting who have a huge range of settings for all players.In this guide, we will go in-depth with the best crosshair settings for VALORANT. That's it for this list with a small selection of pro players. Movement Error: ONFiring Error: ON Fnatic Boaster Valorant CrosshairĬrosshair Code – 0 s 1 P c 1 o 1 d 1 0l 0 0o 2 0a 1 0f 0 1t 0 1l 0 1o 0 1a 0 S c 1 o 1 General ColorĬrosshair Code – 0 s 1 P c 5 h 0 0l 4 0o 2 0a 1 0f 0 1b 0 S c 5 Primary ColorĬrosshair Code – 0 s 1 P c 5 o 1 d 1 z 3 f 0 0t 6 0l 0 0a 1 0f 0 1b 0 S c 6 s 0.949 o 1 ColorĬrosshair Code – 0 s 1 P c 5 h 0 m 1 0l 4 0v 2 0o 0 0a 1 1b 0 S c 4 s 0.8 o 1 Show Spectated Player’s Crosshair: ON Inner Lines While not a great crosshair, we've included it to give the option to reset if you ever want to in future.
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Download shutter encoder2/16/2024 FFmpeg also makes the media processing really very fast. Shutter Encoder leverages another open-source media encoding software called FFmpeg which means that it supports almost all media types available. Based on the options and features selected, it works on your selected media files and places the output in the destination directory. For example, if you select JPEG function, features such as watermark, rotation, crop, color management become available on the right side of the Shutter Encoder.įor all the functions, that you have selected, you have to click on the Start Function button to run it. Depending on the function that you are going to select, we have access to many more features. After that we can select a function that we want to run on those files.Īmong the functions, we have no-conversion functions (Cut without re-encoding, Replace audio, Rewrap, Conform, Merge, Extract, Subtitling, Video inserts), sound conversions, editing codecs, output codecs, broadcast codecs, old codecs, archiving codecs, image creation, burn and rip (DVD, Blu-ray, DVD RIP), analysis, and downloading of videos.Īs soon as you select a function, more features become available and the window becomes enlarged. You have to start by adding the source media files whether they are images, audio files or video files. The user interface of Shutter Encoder is a small window in which all the features are available. If you download the portable version, then the package comes with a version JRE included. It is available in the installer format and also as a portable program. It is designed using Oracle Java and requires JRE to be installed on your system. It offers a large number of functions including the conversion, extraction, merging, video subtitling, DVD ripping, DVD burning and more. Shutter Encoder is a popular video encoding and conversion application.
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2d rocket league2/16/2024 Players drive cars that resemble rocket go-karts. This online game clone provides gameplay comparable to the original "Rocket League" game. As in a typical game, the team that scores the most goals in the allocated time wins. Teams are made up of players who drive radio-controlled automobiles and are guided by real people and artificial intelligence. This sport is not the same as a traditional football game. It's also a free-to-play multiplayer football game inspired by Rocket League. League is a fantastic arcade game where you play actual football while controlling a radio-controlled automobile. The online Rocket League game version provides players with booster-rigged vehicles that can be crashed into balls for fantastic goals or epic saves, as well as the ability to customize your car, take to the pitch, and compete in one of the most competitive leagues. Rocket League is a future sports-action game that blends the speed and realistic mechanics with automobiles and driving. If you like fast sports cars, soccer, and adrenaline-pumping games, then you can play Rocket League unblocked in your browser for free, as well as a variety of other exciting car and truck soccer games. It is only a matter of time before 2D Rocket League becomes a global phenomenon.Rocket League game it's now free online on ! The game is also becoming more competitive, with tournaments and leagues popping up all over the world. The game is constantly being updated and improved, and new features are being added all the time. The Future of 2D Rocket LeagueĢD Rocket League has become a popular game, and it is only getting bigger. You should be careful when downloading mods, as some of them can be malicious. You can find a variety of different mods, such as new cars, maps, and power-ups. Mods are modifications to the game that allow you to change the way it looks and plays. If you want to customize your 2D Rocket League experience, you can download mods. The tournaments usually have different rules and regulations, so you should make sure to read them carefully before entering. These tournaments are held online and you can compete against other players from around the world. If you want to take your 2D Rocket League skills to the next level, you can participate in tournaments. Finally, you should try to outmaneuver your opponents and use the boost to gain an advantage. You should also practice your aim, and focus on scoring goals. You should also learn the different power-ups and how to use them effectively. First, you should practice your controls and become comfortable with the game. If you want to become a better player at 2D Rocket League, there are a few tips you can keep in mind. You should also use the shield to protect yourself from incoming attacks, and you should try to outmaneuver your opponents. You should also be aware of your opponents’ movements, and you should use the boost to gain an advantage over them. You should focus on scoring goals, and you should use power-ups to your advantage. To win at 2D Rocket League, you need to have a good strategy. 2D Rocket League: A New Dimension of Fun Strategies for Winning at 2D Rocket League You can also use power-ups to help you score goals, and you can use the boost to increase your speed or the shield to protect yourself from incoming attacks. The game is played in a three-minute match, and the team with the most goals at the end of the match wins. The rules of 2D Rocket League are similar to the original game, with a few minor changes. You can also use power-ups to help you score goals, such as the Rocket Boost, which gives you a speed boost, or the Shield, which protects you from incoming attacks. You can use the arrow keys or WASD to control your car, and you can boost by pressing the space bar. The goal is to score more goals than your opponents, and you can do this by controlling your car and using power-ups. 2D Rocket League: The Future How to Play 2D Rocket LeagueĢD Rocket League is a fast-paced game that requires quick reflexes and strategy.
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Robert millikan atomic theory2/16/2024 These qualities were valued at Chicago, but not as much as research. In collaboration he wrote elementary texts that educated a generation of Americans, and in the classroom he proved to be an outstanding educator. At Chicago Millikan began work in various areas such as electrical discharges.īut it was as a teacher and textbook writer that Millikan first made his mark. Millikan jumped at it, although he could have had an appointment elsewhere at twice the salary, for Michelson promised that he could spend up to half his time doing his own research, a privilege not granted at most colleges. Michelson, offering him a teaching assistantship at Chicago. While he was there he got a message from A. He next studied in Germany, as was the custom for young American scientists of his generationduring his summer in Gottingen he found more Americans than Germans among the advanced students in the laboratory. Robust and athletic, he considered making a career in physical education until one of his professors persuaded him to go to Columbia University there his real education began. At Oberlin College he taught himself the elements of physics, for nobody there knew enough to teach him. He was of native American stock, raised in the large and cheerful family of an Iowa preacher. Millikan benefited from this trend and worked vigorously to accelerate it. Millikan's lifetime the number of physicists in the United States doubled about every ten years, and the laboratory space and research funds at their disposal grew even faster. Robert Andrews Millikan 1868-1953 Selected Papers HOMEĭuring Robert A.
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Create a work schedule for free template2/16/2024 Were they able to follow and accomplish all of them? Keep your employees even more productive by not overloading them with too much tasks.If there’s one thing that both employees and employers agree with, it’s that time tracking is an extremely tedious process. If you're making a daily work schedule for your employees to follow, then make sure to monitor them at the end of the day. The last step is to monitor and control the schedule. That's the main reason as to why you should be serious in following it and be consistent in updating them from time to time. The main purpose of a schedule is to help you accomplish tasks in a short period of time. What's the point of making a sample schedule in the first place if you're not going to be consistent in following it. By doing this, you are confident that you can accomplish every task given in a short period of time. In making work or shift schedule, it's important that you set a time frame for each task. That's now where the importance of making a work schedule comes into the picture. Statistics show that work overload decreases productivity by 68% in employees who feel they don’t have enough hours in the day to complete their tasks. Place at the top the tasks that need to be urgently finished, and following them would be the less prioritized ones. Chronologically arrange all the activities/tasks according to their priority. Arrange The ActivitiesĪfter determining the activities for the work schedule, it's now time to arrange them accordingly. Arrange and layout them properly in your work schedule so that you will be extra motivated to accomplish them. Define and present the scheduled activities clearly in making a work schedule. Define The Schedule Activitiesīefore you start making your construction/work training schedule in the Excel spreadsheet, try to breakdown first into schedule activities all the tasks that you need to be accomplished for. We have provided a simple guide step below on how you can transform a blank work schedule to a constructive and efficient one. By making a consistent work schedule you get every job done efficiently, you'll be able to accomplish the task on or before its given deadline, it defines work at hand, it greatly helps in achieving work-life balance, and helps you avoid stress. In businesses, maintaining a work schedule/weekly event planner plays a vital role in its success. Whether you are self-employed or work outside of the home, maintaining a consistent work schedule is important for you. On the other hand, a weekly/monthly work schedule chart is usually done alphabetically in order to present clearly all the task that needs to be accomplished within the week/month. A daily work plan schedule is usually arranged in chronological order that helps you stay organized and accomplish personal or business tasks within a day. Schedules, in general, are necessary for the day-to-day operations of many businesses. It often varies depending on the organization and the type of job. There are different types of work schedule, such as daily, weekly, and monthly work schedules. What are you waiting for? Grab the chance to download them now! What Is a Work Schedule?Ī work schedule refers to the days of the week and hours of the day that an employee usually lots of work. If you download our work schedule templates, we assure you that they will be a big help for you because we made them available in different paper sizes. And because your convenience is our top priority, we made sure that our templates are downloadable in all formats of Google Docs, Google Sheets, MS Excel, MS Word, Pages, and Photoshop. Choose from our wide variety of quick and time-saving work schedule templates that would absolutely help you ace every task. Make yourself even more productive with the help of our 100% customizable, printable, easily editable, and high-quality work schedule templates.
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What gene is affected to cause scid2/16/2024 3) demonstrated absence of IL2RG, suggesting that the mutation caused degradation of the molecule. 2), we investigated the expression of members of the IL2/JAK3 signaling pathway by western blot. Since the mutation causes a 42 amino acid truncation of the intracellular domain of the γC, including of the Janus kinase 3 (JAK3) binding site (Fig. Based on this finding, the therapeutic plan of the patient was changed and he became a potential candidate for allogeneic hematopoietic stem cell transplantation. Comparing with the primary immunodeficiency genes database, the only variant consistent with the patient’s immunological phenotype was a novel nonsense mutation, p.R328X (c.982C>T) in exon 8 of the IL2RG gene (Fig. Analysis of all variants were performed according to a standard pipeline described previously we identified 2 homozygous (autosomal) and 5 hemizygous (X-linked) variants which were absent from dbSNP database and 1000 Genome database (Additional file 1: Table S1). As the patient was born in a consanguineous family and showed a family history of recurrent infections and early death on the maternal side, an autosomal recessive or X-linked inheritances pattern was expected. In order to identify the molecular defect, whole exome sequencing (WES) was performed. Despite his combined immunodeficiency, the patient was free from opportunistic infections and his condition improved with temporary substitution of subcutaneous immunoglobulin and prophylactic antibiotics. The observation suggested that PHA and ConA stimulations for CD4 + T cells may be different from CD8 + T cells. However, normal response to mitogens phytohemagglutinin (PHA) and concanavalin A (Con A) by CD4 + T cells, but not CD8 + T cells were detected. The patient had low specific cell-mediated immune response in activated whole blood using mitogens and antigen, such as pokeweed mitogen (PWM), candida antigen etc. Low CD4 + and CD8 + T cell numbers, with normal numbers of B and NK cells were detected (Fig. Although a complete blood count and immunoglobulin levels were normal, lymphocyte populations were measured. Immunologic profiles were investigated as previously described. Here we describe a novel nonsense mutation in the IL2RG gene consisting of a single nucleotide substitution at exon 8, in which a normal count of NK cells was found in peripheral blood.Īt the age of 8 years, a computed tomography was performed due to a progression of his pulmonary disease which revealed bronchiectasis and a right middle lobe atelectasis. ĭue to poorly defined clinical and immunological phenotypes, the diagnosis is usually established later in childhood or even in adulthood, and the appropriate treatment is thus delayed. In addition, some of these patients might not be detected by newborn screening programs for SCID. Some patients might be less susceptible to infections, the reduction of T cells is relatively moderate and a normal lymphocyte proliferation assay may be observed. Several patients having hypomorphic IL2RG mutation with a milder form of combined immunodeficiency, termed “atypical X-SCID”, have been described previously. The disease is usually lethal within the 1st year of life unless reconstitution of the immune system is carried out.ĭifferent mutations in the IL2RG gene have also been shown to be associated with less severe phenotypic variants. Additional features include protracted diarrhea, rash, fever, pneumonia and sepsis. Infants with X-SCID are highly susceptibility to bacterial and opportunistic infections. In typical X-SCID, the disease is characterized by an almost complete absence of T and NK cells, and nearly normal or high numbers of functionally deficient B cells (T –B +NK − phenotype). The variability in the phenotypic spectrum of classic X-SCID associated gene highlights the necessity of multi-disciplinary cooperation vigilance for a more accurate diagnostic workup. This is the first report of an atypical X-SCID phenotype due to an exon 8 mutation in the IL2RG gene. In addition, the characteristics of the mutations previously described in 39 patients with an atypical phenotype were reviewed and analyzed from the literature. Functional impairment of the IL2RG was confirmed by IL2-Janus kinase 3-signal transducer and activator of transcription signaling pathway investigation. We report a 16-year-old patient with a T low B + NK + cellular immunodeficiency due to a novel nonsense mutation in exon 8 (p.R328X) of the IL2RG gene. Due to a leaky clinical phenotype, diagnosis and appropriate treatment are challenging in these patients. Atypical X-linked severe combined immunodeficiency (X-SCID) is a variant of cellular immunodeficiency due to hypomorphic mutations in the interleukin 2 receptor gamma ( IL2RG) gene.
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Freedom planet playable torque2/15/2024 Carol stated that he could be, though he never talked about it. In one point in the story, Torque asked Carol if Spade was also a Prince since he was Dail's brother. Spade is the younger half-brother of Prince Dail, who hired him to steal the Kingdom Stone in order to flush out their father's killer, with details of their relationship and history are currently unknown. Spade, insuring that Dail will cover his expenses Spade can also be cold and vengeful, but in Freedom Planet 2, he appears to have become a bit more charismatic. He also holds grudges, as seen in the way he treats Lilac & Carol after they left the Red Scarves, seeing them as traitors in the years following their desertion. Spade is a rude and smart-aleck individual who's unwilling to listen to words or reason, such as when Lilac tried and failed to tell him of Lord Brevon's involvement in his father's murder. In Freedom Planet 2, he wears a black jacket, white jeans and his ears are colored black and red.įor both outfits, Spade wears a pair of red sunglasses and a Red Scarf, which is also a symbol of his status as a member of the Red Scarves. In Freedom Planet, Spade wear a black sleeveless shirt, brown jeans, black shoes, red biker gloves and an oval belt with a buckle shaped like his namesake. Spade is a white and black panda with green eyes and messy hair. There were numerous designs for Spade's Panda form, with the 6th design being the final version used for Freedom Planet. Spade would undergo a redesign later on, being changed into a Panda. His shoes resembeled the Air Shoes worn by Shadow the Hedgehog, the Rival of Freedom Planet's original inspiration: Sonic the Hedgehog. Spade was first designed as a Cavy (South American Rodent).
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California earthquake map2/15/2024 Only several hundred are stronger than magnitude 3.0, and only about 15 to 20 are greater than magnitude 4.0, according to the USGS.įor the latest news, weather, sports, and streaming video, head to KTLA. Tens of thousands of earthquakes are recorded in California each year however, the vast majority of them are extremely minor. Make a plan to prepare for emergencies at ,” the mayor tweeted. Download scientific diagram Map of historical (M > 2.5) seismicity from the Northern California Earthquake Data Center (NCEDC) catalogue with known active. On July 4., 2019, a magnitude 6.4 earthquake hit the southern California. “This is a reminder that earthquakes can happen at any time. map out surface displacement from the recent California earthquakes. Los Angeles Mayor Karen Bass also reassured residents that the quake, while alarming, did not cause damage, and she also took the opportunity to encourage residents to be prepared. But with a long-term average of about once a month, having two within a week is just normal variability,” she told KTLA. A 6.2 magnitude earthquake off the coast of Northern California rattled a wide swath of the state shortly after noon local time, according to data from the US Geological Survey. “We had a 4.1 on New Year’s Day down by Palos Verdes and then this 4.2. Southern California averages about ten earthquakes with a magnitude of 4.0 or greater every year, so Jones says Friday’s temblor is no cause for alarm. Find all latest earthquakes in California, USA, in our list below, updated every minute Events are often reported within minutes. “In 1970, there was a 5.2 with a 4.0 foreshock in close to the same location,” Jones tweeted. Latest quakes in California, USA, in the past 24 hours on Saturday, December 2, 2023. Lucy Jones, SoCal’s preeminent seismologist, said the earthquake occurred where the San Andreas and San Jacinto faults intersect, which has been the site of previous quakes. |